Cleveland Guardians vs Boston Red Sox: final score and closing oddsTue, Sep 22, 6:45 PM ET

Final score, plus the rest of the MLB schedule and odds.

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Also searched as Cleveland vs Boston, Cleveland Guardians vs Boston Red Sox and Red Sox vs Guardians.

Updated Mon, Nov 9, 10:55 PM ET

Start: Tue, Sep 22, 6:45 PM ET
Venue: Fenway Park

Guardians: 3
Red Sox: 2

About Guardians vs Red Sox

Cleveland Guardians vs Boston Red Sox was played on Tue, Sep 22, 6:45 PM ET at Fenway Park. Final score: Guardians 3, Red Sox 2.

People search this MLB game as Guardians vs Red Sox, Cleveland vs Boston, Cleveland Guardians vs Boston Red Sox, Red Sox vs Guardians, Boston vs Cleveland and Boston Red Sox vs Cleveland Guardians. It is the same game, and this page has its odds.

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Guardians vs Red Sox questions

What was the final score of Guardians vs Red Sox?

Guardians 3, Red Sox 2, on Sep 22, 2026.

Where can I compare Red Sox vs Guardians odds?

Here: this page keeps the closing consensus line from the odds sources we track and how it moved from open to close. The Live Board has every MLB game on one screen.